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Loan and Security Agreements (Details)
1 Months Ended 9 Months Ended 12 Months Ended
Feb. 28, 2015
USD ($)
$ / shares
shares
Dec. 31, 2012
USD ($)
Sep. 30, 2015
USD ($)
installment
Dec. 31, 2014
USD ($)
installment
Loan and Security Agreements        
Repayment of existing debt     $ 15,784,150  
Value of warrants     1,184,228  
Loss on extinguishment of debt     1,035,981  
Secured debt | Oxford Loan        
Loan and Security Agreements        
Loss on extinguishment of debt     $ 1,000,000  
Secured debt | Oxford Loan        
Loan and Security Agreements        
Amount borrowed   $ 15,000,000    
Repayment of existing debt $ 15,500,000      
Fixed interest rate (as a percent)       9.20%
Number of consecutive monthly principal installments | installment       30
Final payment       $ 675,000
Secured debt | Hercules Loan        
Loan and Security Agreements        
Maximum borrowing capacity 25,000,000      
Amount borrowed 16,500,000      
Additional amount available $ 8,500,000      
Number of consecutive monthly principal installments | installment     30  
Final payment     $ 610,500  
Secured debt | Hercules Loan | Minimum        
Loan and Security Agreements        
Fixed interest rate (as a percent)     9.00%  
Secured debt | Hercules Loan | Hercules        
Loan and Security Agreements        
Number of warrants (in shares) | shares 180,274      
Exercise price of warrants (in dollars per share) | $ / shares $ 5.89      
Value of warrants $ 1,200,000      
Secured debt | Hercules Loan | Equity financings | Hercules | Right to participate in future equity financings | Maximum        
Loan and Security Agreements        
Equity financings amount $ 2,000,000      
Secured debt | LIBOR | Oxford Loan        
Loan and Security Agreements        
Variable rate basis       three-month U.S. Libor rate
Variable interest rate margin (as a percent)       8.73%
Secured debt | LIBOR | Oxford Loan | Minimum        
Loan and Security Agreements        
Variable rate base (as a percent)       0.47%
Secured debt | Prime | Hercules Loan        
Loan and Security Agreements        
Variable rate basis     Prime minus 4.25%  
Variable interest rate margin (as a percent)     9.00%  
Variable rate adjustment (as a percent)     4.25%  
Secured debt | First year | Hercules Loan        
Loan and Security Agreements        
Prepayment premium as percentage of outstanding principal     3.00%  
Secured debt | Second year | Hercules Loan        
Loan and Security Agreements        
Prepayment premium as percentage of outstanding principal     2.00%  
Secured debt | After the second year | Hercules Loan        
Loan and Security Agreements        
Prepayment premium as percentage of outstanding principal     1.00%