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Summary of Significant Accounting Policies - Net Loss Per Share (Details) - shares
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Anti-dilutive securities      
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 7,372,631 6,078,234 4,312,445
Common stock warrants      
Anti-dilutive securities      
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 180,274 242,779 242,779
Restricted Stock Units      
Anti-dilutive securities      
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares)   147,554 264,361
Common stock options      
Anti-dilutive securities      
Anti-dilutive securities excluded from the calculation of diluted net loss per share (in shares) 7,192,357 5,687,901 3,805,305