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Organization and Description of Business (Details) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Feb. 29, 2020
Dec. 31, 2019
Dec. 31, 2018
Nature of Operations      
Product revenue   $ 0  
Accumulated deficit   (260,370) $ (241,551)
Cash and cash equivalents   34,479 $ 7,851
Perceptive | Senior secured delayed draw term loan facility | Perceptive Credit Agreement, Tranche One      
Nature of Operations      
Amount borrowed   5,000  
Perceptive | Senior secured delayed draw term loan facility | Perceptive Credit Agreement, Tranche Two      
Nature of Operations      
Amount borrowed   $ 15,000  
Subsequent Event | Perceptive | Senior secured delayed draw term loan facility | Perceptive Credit Agreement      
Nature of Operations      
Maximum borrowing capacity $ 35,000    
Subsequent Event | Perceptive | Senior secured delayed draw term loan facility | Perceptive Credit Agreement, Tranche One      
Nature of Operations      
Amount borrowed 5,000    
Subsequent Event | Perceptive | Senior secured delayed draw term loan facility | Perceptive Credit Agreement, Tranche Two      
Nature of Operations      
Amount borrowed $ 15,000