X0306 4 2017-03-15 0 0001660719 Aralez Pharmaceuticals Inc. ARLZ 0001258673 KOVEN ANDREW I C/O ARALEZ PHARMACEUTICALS INC., 7100 WEST CREDIT AVENUE, SUITE 101 MISSISSAUGA A6 L5N 0E4 ONTARIO, CANADA 0 1 0 0 President & Chief Business Off Common Shares, without par value 2017-03-15 4 P 0 20000 2.546 A 1424236 D This transaction was executed in multiple trades at prices ranging from $2.525 to $2.560. The price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. /s/ Eric L. Trachtenberg, attorney-in-fact for Andrew I. Koven 2017-03-17