Segment Reporting - Segment Loss, Including Significant Segment Expenses (Details) - USD ($) $ in Thousands		3 Months Ended
		Mar. 31, 2026	Dec. 31, 2025	Mar. 31, 2025
Segment Reporting Information [Line Items]
License revenue		$ 1,039		$ 0
Research and development expense	[1]	17,903		10,627
Net loss and comprehensive loss		(23,283)		(15,148)
Net loss and comprehensive loss		(23,283)	$ (23,300)	(15,148)
Reportable Segment
Segment Reporting Information [Line Items]
License revenue		1,039		0
Personnel costs		10,646		3,091
Milestone and license fees		2,500		965
Professional and other fees		3,938		1,736
Other expense (income)		(1,446)		1,148
Net loss and comprehensive loss		(23,283)		(15,148)
Net loss and comprehensive loss		(23,283)		(15,148)
Reportable Segment | CR-001 external research and development costs
Segment Reporting Information [Line Items]
Research and development expense		5,078		6,275
Reportable Segment | CR-002 external research and development costs
Segment Reporting Information [Line Items]
Research and development expense		3,585		1,065
Reportable Segment | Discovery external research and development costs
Segment Reporting Information [Line Items]
Research and development expense		$ 21		$ 868

[1] Includes related party amount of $2,923 and $8,777 for the three months ended March 31, 2026 and March 31, 2025, respectively.