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CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED SHARES AND SHAREHOLDERS' EQUITY (DEFICIT) - USD ($)
$ in Thousands
Total
Reverse Recapitalization Of GlycoMimetics
Series A Preferred Stock
Convertible Notes Payable
Convertible Preferred Stock
Non-Voting Preferred Shares
Non-Voting Preferred Shares
Series A Preferred Stock
Ordinary Shares
Ordinary Shares
Reverse Recapitalization Of GlycoMimetics
Ordinary Shares
Convertible Notes Payable
Additional Paid-in Capital
Additional Paid-in Capital
Reverse Recapitalization Of GlycoMimetics
Additional Paid-in Capital
Convertible Notes Payable
Accumulated Deficit
Beginning balance, Convertible Preferred Stock (in shares) at Sep. 19, 2024         0                  
Beginning balance, Convertible Preferred Stock at Sep. 19, 2024         $ 0                  
Increase (Decrease) in Temporary Equity [Roll Forward]                            
Issuance of Series Seed convertible preferred stock (in shares)         20,000,000                  
Issuance of Series Seed convertible preferred stock         $ 4,000                  
Ending balance, Convertible Preferred Stock (in shares) at Dec. 31, 2024         20,000,000                  
Ending balance, Convertible Preferred Stock at Dec. 31, 2024         $ 4,000                  
Beginning balance (in shares) at Sep. 19, 2024           0                
Beginning balance at Sep. 19, 2024 $ 0         $ 0   $ 0     $ 0     $ 0
Beginning balance (in shares) at Sep. 19, 2024               0            
Increase (Decrease) in Stockholders' Equity [Roll Forward]                            
Issuance of common stock (in shares) [1]               1,018,604            
Issuance of common stock [1] 1,315             $ 1     1,314      
Share-based compensation 1,073                   1,073      
Net loss (17,867)                         (17,867)
Ending balance (in shares) at Dec. 31, 2024     0     0                
Ending balance at Dec. 31, 2024 $ (15,479)         $ 0   $ 1     2,387     (17,867)
Ending balance (in shares) at Dec. 31, 2024 1,018,604             1,018,604            
Increase (Decrease) in Temporary Equity [Roll Forward]                            
Exchange of Series Seed convertible preferred stock for Series A designated non-voting convertible preferred shares upon the closing of the reverse recapitalization (in shares)         (20,000,000)                  
Exchange of Series Seed convertible preferred stock for Series A designated non-voting convertible preferred shares upon the closing of the reverse recapitalization         $ (4,000)                  
Ending balance, Convertible Preferred Stock (in shares) at Dec. 31, 2025         0                  
Ending balance, Convertible Preferred Stock at Dec. 31, 2025         $ 0                  
Increase (Decrease) in Stockholders' Equity [Roll Forward]                            
Issuance of common stock (in shares)               13,664,251            
Issuance of common stock $ 185,000             $ 14     184,986      
Repurchase and cancellation of restricted stock awards (in shares)               (127,889)            
Repurchase and cancellation of restricted stock awards (177)                   (177)      
Conversion of convertible securities (in shares)             2,890   645,274 1,850,790        
Conversion of convertible securities   $ 525 $ 4,000 $ 40,515     $ 4,000     $ 2   $ 525 $ 40,513  
Issuance of common stock and pre-funded warrants in the Pre-Closing financing (in shares)               10,504,926            
Issuance of ordinary shares and pre-funded warrants in the Pre-Closing financing 159,475             $ 11     159,464      
Issuance costs of Pre-closing financing and reverse recapitalization (17,201)                   (17,201)      
Issuance costs of private placement financing (13,065)                   (13,065)      
Issuance of Parascent warrants 4,358                   4,358      
Share-based compensation $ 9,003                   9,003      
Early exercise of stock options (in shares) 811             811            
Net loss $ (153,942)                         (153,942)
Ending balance (in shares) at Dec. 31, 2025     2,890     2,890                
Ending balance at Dec. 31, 2025 $ 203,012         $ 4,000   $ 28     $ 370,793     $ (171,809)
Ending balance (in shares) at Dec. 31, 2025 27,556,767             27,556,767            
[1] Includes issuance of 296,104 restricted stock awards (see Note 10)