X0306 4 2022-11-11 0 0001253689 GLYCOMIMETICS INC GLYC 0001589711 Hahn Brian M. C/O GLYCOMIMETICS, INC. 9708 MEDICAL CENTER DRIVE ROCKVILLE MD 20850 0 1 0 0 SVP Finance, CFO Common Stock 2022-11-11 4 P 0 20000 1.06 A 56843 D The Reporting Person purchased the securities on the open market at purchase prices ranging from $1.03 to $1.15 per share, with a weighted average purchase price of $1.06 per share. The Reporting Person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price. /s/ Brian F. Leaf, attorney-in-fact 2022-11-14