X0306 4 2022-03-09 0 0001253689 GLYCOMIMETICS INC GLYC 0001589711 Hahn Brian M. C/O GLYCOMIMETICS, INC. 9708 MEDICAL CENTER DRIVE ROCKVILLE MD 20850 0 1 0 0 SVP Finance, CFO Common Stock 2022-03-09 4 S 0 2917 1.09 D 36843 D The sales reported on this Form 4 were effected to satisfy tax withholding obligations in connection with the settlement of restricted stock units as part of a "sell to cover" transaction and do not represent discretionary trades by the reporting person. The common stock was sold by the reporting person in a series of open market transactions on the transaction date with a volume weighted average sale price of $1.09. The range of sales prices for the transactions reported was $1.09 to $1.11 per share. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price. /s/ Brian F. Leaf, attorney-in-fact 2022-03-10