X0306 4 2016-01-07 0 0001253689 GLYCOMIMETICS INC GLYC 0001589725 Thackray Helen M. C/O GLYCOMIMETICS, INC. 9708 MEDICAL CENTER DRIVE ROCKVILLE MD 20850 0 1 0 0 VP Clinical Development, CMO Employee Stock Option (right to buy) 5.22 2016-01-07 4 A 0 71000 0.00 A 2026-01-06 Common Stock 71000 71000 D One-fourth of the shares underlying this option vest on January 7, 2017 and the balance of the shares vest in a series of 36 successive equal monthly installments thereafter, subject to the reporting person's continuous service as of each such vesting date. /s/ Brian F. Leaf, attorney-in-fact 2016-01-11