X0306 4 2021-09-10 0 0001253176 VAPOTHERM INC VAPO 0001681006 Dube Joel F. 100 DOMAIN DRIVE EXETER NH 03833 0 1 0 0 Chief Accounting Officer Common Stock 2021-09-10 4 M 0 416 12.16 A 4516 D Common Stock 2021-09-10 4 M 0 580 12.28 A 5096 D Common Stock 2021-09-10 4 S 0 996 29.1 D 4100 D Stock Option (right to buy) 12.16 2021-09-10 4 M 0 416 0 D 2030-01-01 Common Stock 416 4584 D Stock Option (right to buy) 12.28 2021-09-10 4 M 0 580 0 D 2030-01-20 Common Stock 580 6420 D Includes 4,100 shares that will be issued over time upon vesting pursuant to restricted stock units granted under the Vapotherm, Inc. 2018 Equity Incentive Plan. This option is eligible to vest as to 25% of the underlying shares on January 1, 2021, and thereafter, as to the remaining 75% of underlying shares, in 36 monthly installments, provided that the Reporting Person continues to serve as an employee or other service provider to the Issuer on each vesting date and otherwise subject to the Company's applicable equity incentive plan. This option is eligible to vest as to 25% of the underlying shares on December 2, 2020, and thereafter, as to the remaining 75% of underlying shares, in 36 monthly installments, provided that the Reporting Person continues to serve as an employee or other service provider to the Issuer on each vesting date and otherwise subject to the Company's applicable equity incentive plan. /s/ Adrain Bryant, as Attorney In Fact 2021-09-13