X0303 4 2009-11-06 0001170650 MEDCO HEALTH SOLUTIONS INC MHS 0001252004 EPSTEIN ROBERT S 100 PARSONS POND DRIVE FRANKLIN LAKES NJ 07417 1 SVP Medical Affairs & CMO Common Stock 2009-11-06 4 M 0 30000 22.095 A 165637 D Common Stock 2009-11-06 4 S 0 8900 59.0111 D 156737 D Common Stock 2009-11-06 4 S 0 21100 59.679 D 135637 D Common Stock 557 I By 401(k) Stock Option 22.095 2009-11-06 4 M 0 30000 0 D 2015-02-24 Common Stock 30000 15440 D Sale pursuant to 10b5-1 Trading Plan. Represents the weighted average sale price. Sales were executed at prices that ranged from $58.49 to $59.48. Represents the weighted average sale price. Sales were executed at prices that ranged from $59.49 to $59.90. Exercise pursuant to 10b5-1 Trading Plan. The option vests and becomes exercisable in three annual installments beginning February 25, 2006, subject to continued employment. Colleen M. McIntosh, Attorney in Fact 2009-11-09