X0306 4 2018-05-30 0 0001374310 Cboe Global Markets, Inc. CBOE 0001251713 CONCANNON CHRISTOPHER R C/O CBOE GLOBAL MARKETS, INC. 400 SOUTH LASALLE STREET CHICAGO IL 60605 0 1 0 0 President and COO Common Stock 2018-05-30 4 P 0 10000 99.44 A 152526 D The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $99.39 to $99.52. The reporting person undertakes to provide to Cboe Global Markets, Inc., any security holder of Cboe Global Markets, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range. /s/ Laura Zinanni, attorney-in-fact 2018-05-31