X0303 4 2010-01-06 0001070336 ACHILLION PHARMACEUTICALS INC ACHN 0001431443 Clarus Lifesciences II, L.P. C/O CLARUS VENTURES, LLC 101 MAIN STREET, SUITE 1210 CAMBRIDGE MA 02142 0 0 1 0 0001431439 Clarus Ventures II GP, L.P. C/O CLARUS VENTURES, LLC 101 MAIN STREET, SUITE 1210 CAMBRIDGE MA 02142 0 0 1 0 0001431437 Clarus Ventures II, LLC C/O CLARUS VENTURES, LLC 101 MAIN STREET, SUITE 1210 CAMBRIDGE MA 02142 0 0 1 0 0001252523 LIPTAK ROBERT C/O CLARUS VENTURES, LLC 101 MAIN STREET, SUITE 1210 CAMBRIDGE MA 02142 0 0 1 0 0001431403 Simon Nicholas C/O CLARUS VENTURES, LLC 101 MAIN STREET, SUITE 1210 CAMBRIDGE MA 02142 1 0 1 0 0001249153 HENNER DENNIS C/O CLARUS VENTURES, LLC 101 MAIN STREET, SUITE 1210 CAMBRIDGE MA 02142 0 0 1 0 0001252522 GALAKATOS NICHOLAS C/O CLARUS VENTURES, LLC 101 MAIN STREET, SUITE 1210 CAMBRIDGE MA 02142 0 0 1 0 0001431408 Leiden Jeffrey C/O CLARUS VENTURES, LLC 101 MAIN STREET, SUITE 1210 CAMBRIDGE MA 02142 0 0 1 0 0001252525 WHEELER KURT C/O CLARUS VENTURES, LLC 101 MAIN STREET, SUITE 1210 CAMBRIDGE MA 02142 0 0 1 0 0001166285 STEINMETZ MICHAEL C/O CLARUS VENTURES, LLC 101 MAIN STREET, SUITE 1210 CAMBRIDGE MA 02142 0 0 1 0 Common Stock 2010-01-06 4 S 0 49400 3.5027 D 4624167 I By Fund Common Stock 2010-01-07 4 S 0 3600 3.50 D 4620567 I By Fund The sales reported on this Form 4 were effected pursuant to Rule 10b5-1 trading plan adpoted by Clarus Lifesciences II, L.P. (the "Fund") on November 1, 2009. Securities held of record by the Fund. Clarus Ventures II GP, L.P. (the "GPLP"), as the sole general partner of the Fund, may be deemed to beneficially own certain of the shares held of record by the Fund. The GPLP disclaims beneficial ownership of all shares held of record by the Fund in which the GPLP does not have an actual pecuniary interest. Clarus Ventures II, LLC (the "GPLLC"), as the sole general partner of the GPLP, may be deemed to beneficially own certain of the shares held of record by the Fund. Each of Messrs. Galakatos, Henner, Leiden, Liptak, Simon, Steinmetz and Wheeler, as individual Managing Directors of the GPLLC, may be deemed to beneficially own certain of the shares held of record by the Fund. Each of Messrs. Galakatos, Henner, Leiden, Liptak, Simon, Steinmetz and Wheeler disclaims beneficial ownership of all shares held of record by the Fund in which he does not have an actual pecuniary interest. ___________________________________ Robert Liptak, Manager of Clarus Ventures II, LLC, general partner of Clarus Ventures II GP, L.P., general partner of Clarus Lifesciences II, L.P. 2010-01-08 ___________________________________ Robert Liptak, Maganer of Clarus Ventures II, LLC, general partner of Clarus Ventures II GP, L.P. 2010-01-08 ___________________________________ Robert Liptak, Manager of Clarus Ventures II, LLC 2010-01-08 ___________________________________ Robert Liptak, as attorney-in-fact for Nicholas Simon 2010-01-08 ___________________________________ Robert Liptak 2010-01-08 ___________________________________ Robert Liptak, as attorney-in-fact for Dennis Henner 2010-01-08 ___________________________________ Robert Liptak, as attorney-in-fact for Nicholas Galakatos 2010-01-08 ___________________________________ Robert Liptak, as attorney-in-fact for Jeffrey Leiden 2010-01-08 ___________________________________ Robert Liptak, as attorney-in-fact for Kurt Wheeler 2010-01-08 ___________________________________ Robert Liptak, as attorney-in-fact for Michael Steinmetz 2010-01-08