144 0001248093 XXXXXXXX LIVE 0001515673 Ultragenyx Pharmaceutical Inc. 001-36276 60 LEVERONI COURT NOVATO CA 94949 415-483-8800 KAKKIS EMIL D Officer COMMON MERRILL LYNCH

555 CALIFORNIA STREET 9TH FL SAN FRANCISCO CA 94104

25000 1062100.00 92501126 02/28/2025 NASDAQ COMMON 04/27/2010 FOUNDERS SHARES ULTRAGENYX PHARMACEUTICAL, INC N 18256 04/27/2010 CASH COMMON 08/28/2017 STOCK BONUS ULTRAGENYX PHARMACEUTICAL, INC N 1454 08/28/2017 CASH COMMON 09/11/2019 STOCK BONUS ULTRAGENYX PHARMACEUTICAL, INC N 5000 09/11/2019 CASH COMMON 04/29/2022 STOCK BONUS ULTRAGENYX PHARMACEUTICAL, INC N 290 04/29/2022 CASH N EMIL KAKKIS

555 CALIFORNIA STREET 9TH FLOOR SAN FRANCISCO CA 94104

COMMON 12/10/2024 8273 413650.00 EMIL KAKKIS

555 CALIFORNIA STREET, 9TH FLOOR SAN FRANCISCO CA 94109

COMMON 12/30/2024 11727 495264.00 02/28/2025 03/01/2024 EMIL KAKKIS