X0306 4 2020-12-28 0 0001770787 10x Genomics, Inc. TXG 0001246406 CRUTCHFIELD BRADFORD C/O 10X GENOMICS, INC. 6230 STONERIDGE MALL ROAD PLEASANTON CA 94588 0 1 0 0 Chief Commercial Officer Class A Common Stock 2020-12-28 4 M 0 20312 1.20 A 21275 D Class A Common Stock 2020-12-28 4 M 0 13333 5.04 A 34608 D Stock Option (right to buy) 1.20 2020-12-28 4 M 0 20312 0.00 D 2027-10-18 Class A Common Stock 20312 4688 D Stock Option (right to buy) 5.04 2020-12-28 4 M 0 13333 0.00 D 2028-11-02 Class A Common Stock 13333 111667 D This option, originally for 25,000 shares, of which 20,312 shares have been exercised, vested as to one forty-eighth of the shares on October 1, 2017 and one forty-eighth of the shares subject to the option vest each month thereafter, subject to the Reporting Person continuing as a service provider through each such date. This option, originally for 125,000 shares, of which 13,333 shares have been exercised, vested as to one forty-eighth of the shares on October 1, 2018 and one forty-eighth of the shares subject to the option vest each month thereafter, subject to the Reporting Person continuing as a service provider through each such date. /s/ Eric S. Whitaker, as Attorney-in-Fact 2020-12-30