X0303 4 2010-03-05 0 0000887359 AASTROM BIOSCIENCES INC ASTM 0001242613 MAYLEBEN TIMOTHY M PO BOX 376 ANN ARBOR MI 48106 1 1 0 0 CEO, President, CFO & Director Common Stock 2010-03-05 4 P 0 17206 1.452 A 18068 D Common Stock 2010-03-08 4 P 0 16750 1.47 A 34818 D The price reported in column 4 is a weighted average price. The shares were purchased in multiple transactions at prices ranging from $1.45 to $1.46, inclusive. The Reporting Person undertakes to provide Aastrom Biosciences, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the range set forth in this footnote (1). Reflects a 1-for-8 reverse stock split which became effective on February 18, 2010. /s/ Julie A. Caudill, attorney in fact 2010-03-09