X0304 4 2011-08-05 0 0000887359 AASTROM BIOSCIENCES INC ASTM 0001242613 MAYLEBEN TIMOTHY M C/O AASTROM BIOSCIENCES, INC. P.O. BOX 376 ANN ARBOR MI 48106 1 1 0 0 President and CEO Common Stock 2011-08-05 4 P 0 20000 2.36 A 123000 D The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.31 to $2.40, inclusive. The reporting person undertakes to provide to Aastrom Biosciences, Inc., any security holder of Aastrom Biosciences, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price. /s/ Timothy M. Mayleben 2011-08-08