X0201 4 2003-12-22 0 0001027702 EPIX MEDICAL INC EPIX 0001240387 CARPENTER ALAN P JR C/O EPIX MEDICAL, INC. 71 ROGERS STREET CAMBRIDGE MA 02138 0 1 0 0 Exec. VP of Research & Develop Common Stock (Sale Pursuant to a 10b5-1 Trading Plan) 2003-12-22 4 S 0 1000 16.10 D 0 D Common Stock (Sale Pursuant to a 10b5-1 Trading Plan) 2003-12-22 4 S 0 300 16.11 A 0 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on November 26, 2003. Paula Valencia-Galbraith, Attorney-in-Fact 2003-12-24