-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 FDSuH2k7kNxvcZKJBLlxyhZkho4s8aVG6vYzDDv2ZOiVLTxjoxVAjTbR62CcrhuM
 QO+TTUexX/7fKqr1nnCaXQ==

<SEC-DOCUMENT>0000930413-07-006307.txt : 20070730
<SEC-HEADER>0000930413-07-006307.hdr.sgml : 20070730
<ACCEPTANCE-DATETIME>20070730161115
ACCESSION NUMBER:		0000930413-07-006307
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20070726
FILED AS OF DATE:		20070730
DATE AS OF CHANGE:		20070730

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			TETRAGENEX PHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0001362659
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				223781895
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		1 MAYNARD DRIVE, SUITE 205
		CITY:			PARK RIDGE
		STATE:			NJ
		ZIP:			07656
		BUSINESS PHONE:		(201) 505-1300

	MAIL ADDRESS:	
		STREET 1:		1 MAYNARD DRIVE, SUITE 205
		CITY:			PARK RIDGE
		STATE:			NJ
		ZIP:			07656

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			COMER WILLIAM T
		CENTRAL INDEX KEY:			0001240117

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-52292
		FILM NUMBER:		071009667

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		8588602500

	MAIL ADDRESS:	
		STREET 1:		5820 NANCY DRIVE,
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>c49595_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2007-07-26</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001362659</issuerCik>
        <issuerName>TETRAGENEX PHARMACEUTICALS, INC.</issuerName>
        <issuerTradingSymbol>TTRX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001240117</rptOwnerCik>
            <rptOwnerName>COMER WILLIAM T</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>P.O. BOX 2007</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>RANCHO SANTA FE</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92067</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Option</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>1</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2007-07-26</value>
            </transactionDate>
            <deemedExecutionDate>
                <value>2007-07-26</value>
            </deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionTotalValue>
                    <value>350000</value>
                </transactionTotalValue>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F2"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityValue>
                    <value>350000</value>
                </underlyingSecurityValue>
            </underlyingSecurity>
            <postTransactionAmounts>
                <valueOwnedFollowingTransaction>
                    <value>643125</value>
                </valueOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">These options are exerciseable on 7/26/07.</footnote>
        <footnote id="F2">These options expire on 7/26/17.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>William T. Comer</signatureName>
        <signatureDate>2007-07-26</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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