<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3/A</documentType>

    <periodOfReport>2006-02-08</periodOfReport>

    <dateOfOriginalSubmission>2006-02-08</dateOfOriginalSubmission>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001292470</issuerCik>
        <issuerName>NightHawk Radiology Holdings Inc</issuerName>
        <issuerTradingSymbol>NHWK</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001239366</rptOwnerCik>
            <rptOwnerName>CHUNG PETER Y</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O SUMMIT PARTNERS</rptOwnerStreet1>
            <rptOwnerStreet2>222 BERKELEY STREET, 18TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>BOSTON</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02116</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <officerTitle></officerTitle>
            <otherText>Indirect GP of 10% Owner</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable></nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Stock Option - Right to Buy</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>1.56</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2005-04-01</value>
            </exerciseDate>
            <expirationDate>
                <value>2014-10-27</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>36000</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The original Form 3 filed on February 8, 2006 mistakenly reported the 36,000 shares described herein as 22,000 shared of Series A Preferred Stock.</footnote>
        <footnote id="F2">The option became exercisable as to one-third of the total shares (12,000) on April 1, 2005, and subsequently become exercisable each monthly anniversary thereafter at the rate of 1/36th of the total shares. As of the date of the Issuer's IPO, an aggregate of 22,000 shares were vested.</footnote>
    </footnotes>

    <remarks>Summit Partners, L.P. is the managing member of Summit Partners VI (GP), LLC, which is the general partner of Summit Partners VI (GP), L.P., which is the general partner of each of Summit Ventures VI-A, L.P., Summit Ventures VI-B, L.P., Summit VI Advisors Fund, L.P., Summit VI Entrepreneurs Fund, L.P. and Summit Investors VI, L.P. Summit Partners, L.P. is the managing member of Stamps, Woodsum &amp; Co, IV, which is the general partner of Summit Partners SD II, LLC, which is the general partner of Summit Subordinated Debt Fund, L.P. Summit Partners, L.P. has voting and dispositive authority over the shares held by each of these entities and, therefore, may beneficially own such shares. Each of Summit Partners, L.P., Summit Partners VI (GP), LLC, Summit Partners VI (GP), L.P., Summit Partners SD II, LLC, and Summit Master Company, LLC, which is the general partner of Summit Partners, L.P., disclaims beneficial ownership of such shares, except to the extent of its pecuniary interest. Mr. Chung is a member of Summit Master Company, LLC, which is the general partner of Summit Partners, L.P. Mr. Chung disclaims beneficial ownership of such shares, except to the extent of his or its pecuniary interest therein.</remarks>

    <ownerSignature>
        <signatureName>Robin W. Devereux, Power of Attorney for Peter Y. Chung</signatureName>
        <signatureDate>2006-02-28</signatureDate>
    </ownerSignature>
</ownershipDocument>
