-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 yUjOCBsqQ4Hv5bL+gf8qHA==

<SEC-DOCUMENT>0001193805-05-001480.txt : 20050701
<SEC-HEADER>0001193805-05-001480.hdr.sgml : 20050701
<ACCEPTANCE-DATETIME>20050701120223
ACCESSION NUMBER:		0001193805-05-001480
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050623
FILED AS OF DATE:		20050701
DATE AS OF CHANGE:		20050701

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			GENTA INC DE/
		CENTRAL INDEX KEY:			0000880643
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				330326866
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		TWO CONNELL DRIVE
		STREET 2:		..
		CITY:			BERKELEY HEIGHTS
		STATE:			NJ
		ZIP:			07922
		BUSINESS PHONE:		(908) 286-9800

	MAIL ADDRESS:	
		STREET 1:		TWO CONNELL DRIVE
		STREET 2:		..
		CITY:			BERKELEY HEIGHTS
		STATE:			NJ
		ZIP:			07922

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			TATTLE PETER T
		CENTRAL INDEX KEY:			0001239001

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-19635
		FILM NUMBER:		05931317

	BUSINESS ADDRESS:	
		STREET 1:		CATALINA MARKETING CORP
		STREET 2:		200 CARILLON PARKWAY
		CITY:			ST PETERSBURG
		STATE:			FL
		ZIP:			33716
		BUSINESS PHONE:		7275795000

	MAIL ADDRESS:	
		STREET 1:		200 CARILLON PARKWAY
		CITY:			ST PETERSBURG
		STATE:			FL
		ZIP:			33761
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>e500773_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-06-23</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000880643</issuerCik>
        <issuerName>GENTA INC DE/</issuerName>
        <issuerTradingSymbol>GNTA</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001239001</rptOwnerCik>
            <rptOwnerName>TATTLE PETER T</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O GENTA INCORPORATED</rptOwnerStreet1>
            <rptOwnerStreet2>TWO CONNELL DRIVE</rptOwnerStreet2>
            <rptOwnerCity>BERKELEY HEIGHTS</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>07922</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Options to acquire Common Stock</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>1.11</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-06-23</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>10000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2005-06-23</value>
            </exerciseDate>
            <expirationDate>
                <value>2015-06-23</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock, par value $.001</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>10000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">These options were granted pursuant to Genta's Compensation  Plan and vest on the date of the grant. Genta Incorporated
 Directors receive an annual option grant of 20,000 shares.  As Mr. Tattle retired from the Board effective June 30, 2005,
 the grant has been pro-rated for the period January 1 - June 30, 2005.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ PETER T. TATTLE</signatureName>
        <signatureDate>2005-07-01</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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