X0201 42003-10-0100000729922OSI PHARMACEUTICALS INC OSIP0001238974GRANNER DARYL KC/O OSI PHARMACEUTICALS, INC.58 SOUTH SERVICE ROAD, SUITE 110MELVILLENY117471000Common Stock2003-10-014M050005.25A9993DCommon Stock2003-10-014S0500032.35D4993DCommon Stock2003-10-014D04160D4577DStock Option (Right to Buy)5.252003-10-014M050000D1999-06-182008-06-17Common Stock50000DReflects a partial forfieture of restricted stock un the Stock Purchase Plan for Non-Employee Directors.Not Applicable.One third of the stock option became exercisable one year after the date of the grant and the remainder vested ratably on a monthly basis over the succeeding 24 months.The stock option was granted pursuant to one of the Issuer's incentive and non-qualified stock option plans and is exempt under Rule 16b-3.Includes only options with the same termination date.Robert L. Van Nostrand by Power of Attorney2003-10-03