X0306 4 2016-06-07 0 0001416792 Relypsa Inc RLYP 0001238403 SPIEGELMAN DANIEL K C/O RELYPSA, INC. 100 CARDINAL WAY REDWOOD CITY CA 94063 1 0 0 0 Common Stock 2016-06-07 4 S 0 1013 19.3106 D 1237 D Represents shares automatically sold pursuant to the applicable Restricted Stock Unit Award Agreement to satisfy tax withholding obligations in connection with the vesting of Restricted Stock Units and delivery of shares. The price reported in Column 4 is a weighted average sale price. These shares were sold in multiple transactions at prices ranging from $19.26 to $19.38, inclusive. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote. /s/ Ronald A. Krasnow, as Attorney-in-Fact for Daniel K. Spiegelman 2016-06-08