X0306 4 2019-06-04 0 0001346830 Cara Therapeutics, Inc. CARA 0001237624 VOGELBAUM MARTIN C/O RHO VENTURES 152 WEST 57TH STREET, 23RD FLOOR NEW YORK NY 10019 1 0 0 0 Common Stock 2019-06-04 4 A 0 6000 0.00 A 6000 D Common Stock 3068057 I By Partnership Stock Option (Right to Buy) 20.44 2019-06-04 4 A 0 9000 0.00 A 2029-06-04 Common Stock 9000 9000 D Represents the number of shares underlying restricted stock units ("RSUs") granted to the Reporting Person pursuant to the Issuer's non-employee director compensation policy. Each RSU represents the contingent right to receive one share of common stock of the Issuer. The RSUs vest on the earlier of (i) June 4, 2020 and (ii) immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in each case, subject to the Reporting Person's continued service as a director through such date. These securities are owned directly by Ventures. RMV VI, L.L.C. ("RMV") is the general partner of Ventures and Rho Capital Partners LLC ("Partners") is the managing member of RMV. Mark Leschly, Habib Kairouz and Joshua Ruch are managing members of Partners and exercise shared voting and investment power with respect to the shares owned by Ventures. The Reporting Person, a member of the Board of Directors of the Issuer, is a non-managing member of RMV and, as such, advises Ventures with respect to voting and investment decisions relating to the shares of stock owned by Ventures but does not have or share voting and investment power over such shares. The Reporting Person disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein. This option was granted to the Reporting Person pursuant to the Issuer's non-employee director compensation policy. The shares underlying the option vest and become exercisable on the earlier of (i) June 4, 2020 and (ii) immediately prior to the Issuer's next annual meeting of stockholders following the grant date, in each case, subject to the Reporting Person's continued service as a director through such date. /s/Darren DeStefano, Attorney-in-Fact 2019-06-06