X0303 4 2009-09-14 0000901219 HUMAN GENOME SCIENCES INC HGSI 0001237409 BARABE TIMOTHY C 14200 SHADY GROVE ROAD ROCKVILLE MD 20850 1 Chief Financial Officer Common Stock 2009-09-14 4 S 0 35273 20 D 10000.84 D Includes 5,273 shares acquired under the HGSI Employee Stock Purchase Plan as follows: 6/29/2007- 1,992 shares, 6/30/2008- 2,281 shares, 6/30/2009- 1,000 shares. This sale is i/a/w 10b5-1 trading plan effective 8/25/09 Timothy Barabe 2009-09-14