X0202 4 2007-10-04 0 0001019695 ARQULE INC ARQL 0001237404 HILL STEPHEN A C/O ARQULE, INC. 19 PRESIDENTIAL WAY WOBURN MA 01801 1 1 0 0 President and CEO Employee Stock Options 13.62 2007-10-04 4 D 0 40000 D 2012-01-25 Common Stock 40000 0 D Employee Stock Options 13.62 2007-10-04 4 A 0 40000 A 2011-06-30 Common Stock 40000 40000 D Employee Stock Options 3.08 2007-10-04 4 D 0 60000 D 2013-01-16 Common Stock 60000 0 D Employee Stock Options 3.08 2007-10-04 4 A 0 60000 A 2011-06-30 Common Stock 60000 60000 D Employee Stock Options 5.36 2007-10-04 4 D 0 150000 D 2014-01-15 Common Stock 150000 0 D Employee Stock Option 5.36 2007-10-04 4 A 0 150000 A 2011-06-30 Common Stock 150000 150000 D Employee Stock Options 6.31 2007-10-04 4 D 0 125000 D 2015-01-19 Common Stock 125000 0 D Employee Stock Options 6.31 2007-10-04 4 A 0 125000 A 2011-06-30 Common Stock 125000 125000 D Employee Stock Option 5.73 2007-10-04 4 D 0 150000 D 2016-01-19 Common Stock 150000 0 D Employee Stock Options 5.73 2007-10-04 4 A 0 150000 A 2011-06-30 Common Stock 150000 150000 D Employee Stock Options 6.16 2007-10-04 4 D 0 150000 D 2017-01-16 Common Stock 150000 0 D Employee Stock Options 6.16 2007-10-04 4 A 0 150000 A 2011-06-30 Common Stock 150000 150000 D Employee Stock Options 4.625 2007-10-04 4 D 0 320000 D 2009-04-01 Common Stock 320000 0 D Employee Stock Options 4.625 2007-10-04 4 A 0 320000 A 2009-04-01 Common Stock 320000 320000 D Employee Stock Options 20.06 2007-10-04 4 D 0 40000 D 2010-03-16 Common Stock 40000 0 D Employee Stock Options 20.06 2007-10-04 4 A 0 40000 A 2010-03-16 Common Stock 40000 40000 D Employee Stock Options 10 2007-10-04 4 D 0 80000 D 2011-03-22 Common Stock 80000 0 D Employee Stock Options 10 2007-10-04 4 A 0 80000 A 2011-03-22 Common Stock 80000 80000 D Amendment of outstanding option resulting in deemed cancellation of option and grant of replacement option. The option was originally granted on January 25, 2002 and provides for vesting in four equal installments commencing on January 25, 2003. The amendment will extend the post termination expiration date to the earlier of the tenth anniversary of the date of grant of the option or June 30, 2011. Amendment of outstanding option resulting in deemed cancellation of option and grant of replacement option. The option was originally granted on January 16, 2003 and provides for vesting in four equal installments commencing on January 16, 2004. The amendment will extend the post termination expiration date to the earlier of the tenth anniversary of the date of grant of the option or June 30, 2011. Amendment of outstanding option resulting in deemed cancellation of option and grant of replacement option. The option was originally granted on January 15, 2004 and provides for vesting in four equal installments commencing on January 15, 2005. The amendment will extend the post termination expiration date to the earlier of the tenth anniversary of the date of grant of the option or June 30, 2011. Amendment of outstanding option resulting in deemed cancellation of option and grant of replacement option. The option was originally granted on January 19, 2005 and provides for vesting in four equal installments commencing on January 19, 2006. The amendment will extend the post termination expiration date to the earlier of the tenth anniversary of the date of grant of the option or June 30, 2011. Amendment of outstanding option resulting in deemed cancellation of option and grant of replacement option. The option was originally granted on January 19, 2006 and provides for vesting in four equal installments commencing on January 19, 2007. The amendment will extend the post termination expiration date to the earlier of the tenth anniversary of the date of grant of the option or June 30, 2011. Amendment of outstanding option resulting in deemed cancellation of option and grant of replacement option. The option was originally granted on January 16, 2007and provides for vesting in four equal installments commencing on January 16, 2008. The amendment will extend the post termination expiration date to the earlier of the tenth anniversary of the date of grant of the option or June 30, 2011. Amendment of outstanding option resulting in deemed cancellation of option and grant of replacement option. The option was originally granted on April 1, 1999 and provides for vesting in four equal installments commencing on April 1, 2000. The amendment will extend the post termination expiration date to the earlier of the tenth anniversary of the date of grant of the option or June 30, 2011. Amendment of outstanding option resulting in deemed cancellation of option and grant of replacement option. The option was originally granted on March 16, 2000 and provides for vesting in four equal installments commencing on March 16, 2001. The amendment will extend the post termination expiration date to the earlier of the tenth anniversary of the date of grant of the option or June 30, 2011. Amendment of outstanding option resulting in deemed cancellation of option and grant of replacement option. The option was originally granted on March 22, 2001 and provides for vesting in four equal installments commencing on March 22, 2002. The amendment will extend the post termination expiration date to the earlier of the tenth anniversary of the date of grant of the option or June 30, 2011. Employee stock option grant. Robert J. Connaughton, Jr., by Power of Attorney for Stephen A. Hill 2007-10-09