144 0001237401 XXXXXXXX LIVE 0001447028 Arbutus Biopharma Corporation 001-34949 701 Veterans Circle Warminster PA 18974 267-469-0914 David C. Hastings Officer Common Shares Morgan Stanley Wealth Management Canada

140 4th Ave. SW Suite 2740 Calgary A0 T2P3N3

22183 72826.79 159724 02/04/2025 NASDAQ Common Shares 02/03/2025 Restricted Stock Unit Vesting Issuer N 22183 02/03/2025 Compensation Y Shares to be sold to cover witholding taxes upon vesting of restricted stock units. 02/04/2025 03/06/2023 /s/ David C. Hastings