X0203 3 2008-10-30 0 0001408808 PEPLIN INC PLIN 0001383391 New Enterprise Associates 12, Limited Partnership 1119 ST. PAUL STREET BALTIMORE MD 21202 0 0 1 0 0001383390 NEA Partners 12, Limited Partnership 1119 ST. PAUL ST. BALTIMORE MD 21202 0 0 1 0 0001383389 NEA 12 GP, LLC 1119 ST. PAUL ST. BALTIMORE MD 21202 0 0 1 0 0001005544 NEWHALL CHARLES W III 1119 ST. PAUL STREET BALTIMORE MD 21202 0 0 1 0 0001005550 KRAMLICH C RICHARD 1119 ST. PAUL STREET BALTIMORE MD 21202 0 0 1 0 0001005561 BARRIS PETER J 1119 ST. PAUL STREET BALTIMORE MD 21202 0 0 1 0 0001062466 PERRY MARK W 1119 ST. PAUL STREET BALTIMORE MD 21202 0 0 1 0 0001219855 BARRETT M JAMES 1119 ST. PAUL STREET BALTIMORE MD 21202 0 0 1 0 0001237289 SANDELL SCOTT D 1119 ST. PAUL STREET BALTIMORE MD 21202 0 0 1 0 0001172932 TRAINOR III EUGENE A 1119 ST. PAUL STREET BALTIMORE MD 21202 0 0 1 0 Common Stock 1286563 D Common Stock Warrant (Right to Buy) 7.86 2008-10-23 2013-10-23 Common Stock 264608 D The shares are directly held by New Enterprise Associates 12, Limited Partnership ("NEA 12") and indirectly held by NEA Partners 12, Limited Partnership ("NEA Partners 12"), the sole general partner of NEA 12, NEA 12 GP, LLC ("NEA 12 GP"), the sole general partner of NEA Partners 12, and the individual managers of NEA 12 GP (NEA Partners 12, NEA 12 GP and the individual managers of NEA 12 GP together, the "Indirect Reporting Persons"). The individual managers of NEA 12 GP are M. James Barrett, Peter J. Barris, Forest Baskett, Ryan D. Drant, Patrick J. Kerins, C. Richard Kramlich, Krishna "Kittu" Kolluri, Charles M. Linehan, Charles W. Newhall III, Mark W. Perry, Scott D. Sandell and Eugene A. Trainor III. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 12 shares in which the Indirect Reporting Persons have no actual pecuniary interest. The securities are directly held by NEA 12 and indirectly held by the Indirect Reporting Persons. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 12 securities in which the Indirect Reporting Persons have no actual pecuniary interest. /s/ Louis Citron, attorney-in-fact 2008-10-30