X0306 4 2017-06-01 1 0001532063 Express Scripts Holding Co. ESRX 0001235682 Paz George C/O EXPRESS SCRIPTS HOLDING COMPANY ONE EXPRESS WAY ST. LOUIS MO 63121 1 0 0 0 Common Stock 2017-06-01 4 M 0 69847 A 960401 D Common Stock 2017-06-01 4 F 0 31851 60.40 D 928550 D Common Stock 2018-11-28 5 G 0 100000 0 D 828550 D Common Stock 2018-12-20 4 D 0 828550 D 0 D Common Stock 2018-12-20 4 D 0 132527 D 0 I By Spouse Trust Common Stock 2018-12-20 4 D 0 132850 D 0 I By Reporting Person's Trust Phantom Stock Units 2017-06-01 4 M 0 69847 D 2017-06-01 2017-06-01 Express Scripts Holding Company Common Stock 69847 0 D Non-Qualified Stock Option (Right to Buy) 53.50 2018-12-20 4 D 0 209358 0 D 2019-02-27 Express Scripts Holding Company Common Stock 209358 0 D Non-Qualified Stock Units (Right to Buy) 58.17 2018-12-20 4 D 0 210091 0 D 2020-03-06 Express Scripts Holding Company Common Stock 210091 0 D Non-Qualified Stock Option (Right to Buy) 77.15 2018-12-20 4 D 0 221506 0 D 2021-03-05 Express Scripts Holding Company Common Stock 221506 0 D Non-Qualified Stock Option (Right to Buy) 84.83 2018-12-20 4 D 0 189385 0 D 2025-03-04 Express Scripts Holding Company Common Stock 189385 0 D Non-Qualified Stock Option (Right to Buy) 69.57 2018-12-20 4 D 0 249770 0 D 2026-03-09 Express Scripts Holding Company Common Stock 249770 0 D Non-Qualified Stock Option (Right to Buy) 60.66 2018-12-20 4 D 0 8006 0 D 2027-05-11 Express Scripts Holding Company Common Stock 8006 0 D Each share of phantom stock was the economic equivalent of one share of the Issuer's common stock. The Reporting Person settled his shares of phantom stock for shares of the Issuer's common stock. Represents shares tendered to Company to cover Reporting Person's tax liability due upon conversion of phantom stock previously awarded under deferred compensation plans. Pursuant to the agreement and plan of merger ("Merger Agreement") between the Issuer and Cigna Corporation, Halfmoon Parent, Inc., Halfmoon I, Inc. and Halfmoon II, Inc., upon closing of the merger of Halfmoon II, Inc. with and into the Issuer (the "Merger"), each common share of the Issuer was converted into the right to receive 0.2434 shares of Halfmoon Parent, Inc. common stock and $48.75 in cash. Each restricted stock unit granted to the Reporting Person in his capacity as a director of the Issuer was converted into a right to receive a cash payment in accordance with the payment ratio set forth in the Merger Agreement. Each restricted stock unit granted to the Reporting Person in his capacity as an executive officer of the Issuer was converted into a unit with respect to common stock of Halfmoon Parent, Inc. in accordance with the exchange ratio set forth in the Merger Agreement. The options vest on varying dates pursuant to the terms of the plans and/or agreements under which they were granted. Pursuant to the Merger Agreement, upon closing of the Merger, the option was converted into an option to purchase common shares of Halfmoon Parent, Inc. in accordance with the exchange ratio set forth in the Merger Agreement. /s/ Nick H. Varsam, as Attorney-in-Fact for George Paz 2018-12-21