Accrued Expenses (Tables)

12 Months Ended

Dec. 31, 2017

Payables and Accruals [Abstract]

Schedule of accrued expenses

As of December 31, 2017 and 2016, accrued expenses consisted of the following (in thousands):

	2017		2016
Accrued contract research and manufacturing costs	$	8,843	$	12,338
Accrued compensation	8,743		9,414
Accrued professional fees	2,429		3,979
Other	513		1,135
Total accrued expenses	$	20,528	$	26,866