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Summary of Significant Accounting Policies - Net loss per common share (Details) - shares
3 Months Ended 9 Months Ended
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Outstanding Stock options        
Weighted-average anti-dilutive shares related to:        
Antidilutive securities excluded from computation of earnings per share (in shares) 6,826,000 2,690,000 6,880,000 4,341,000
Restricted stock awards        
Weighted-average anti-dilutive shares related to:        
Antidilutive securities excluded from computation of earnings per share (in shares) 1,500,000 457,000 1,052,000 547,000
Performance-based restricted stock awards, M356        
Weighted-average anti-dilutive shares related to:        
Antidilutive securities excluded from computation of earnings per share (in shares)     1,439,985