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Collaboration and License Agreements (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended 15 Months Ended 33 Months Ended
Feb. 28, 2015
USD ($)
Jul. 31, 2006
USD ($)
$ / shares
shares
Sep. 30, 2015
USD ($)
Jun. 30, 2015
USD ($)
Sep. 30, 2014
USD ($)
Sep. 30, 2015
USD ($)
item
Sep. 30, 2014
USD ($)
Jun. 30, 2015
USD ($)
Sep. 30, 2011
Mar. 31, 2015
Collaboration revenues:                    
Product revenue     $ 8,666   $ 4,714 $ 30,693 $ 15,216      
Research and development revenue                    
Regulatory and commercial milestones           20,000        
Amortization of upfront payments     2,442   888 6,572 2,789      
Research and development services (FTEs) and external costs     2,687   3,734 9,993 13,066      
Total research and development revenue     5,129   4,622 36,565 15,855      
Total collaboration revenue     13,795   9,336 67,258 31,071      
Operating expenses:                    
Research and Development Expense     525   4,133 2,287 12,975      
General and Administrative Expense     308   341 1,273 824      
Total Operating expenses     833   4,474 3,560 13,799      
2003 Sandoz Collaboration                    
Collaboration revenues:                    
Product revenue         4,714 2,843 15,216      
Research and development revenue                    
Research and development services (FTEs) and external costs     69   195 450 796      
Total research and development revenue     69   195 450 796      
Total collaboration revenue     69   4,909 3,293 16,012      
Operating expenses:                    
Research and Development Expense         50 208 134      
General and Administrative Expense     104   15 326 110      
Total Operating expenses     104   65 $ 534 244      
Percentage of contractual profits earned under collaborative arrangement                 45.00%  
Percentage of royalty for net sales up to pre-defined sales threshold                   10.00%
Percentage of royalty for net sales above pre-defined sales threshold                   12.00%
Percentage of royalty based on contractually defined profits on sales           50.00%        
Maximum percentage of reduction of profit-share, royalty and milestone payments from Sandoz at each quarter           50.00%        
Payment of total annual adjustment through reduction in product revenue       $ 100            
Reduction in product revenue due to netting of shared development and other expenses               $ 1,900    
Collaborative Arrangement, carry forward to future periods           $ 1,800        
Number of significant deliverables identified in arrangement | item           2        
Second Sandoz Collaboration Agreement                    
Collaboration revenues:                    
Product revenue     8,666     $ 27,850        
Research and development revenue                    
Regulatory and commercial milestones           20,000        
Amortization of upfront payments         121   480      
Research and development services (FTEs) and external costs     742   944 2,220 1,738      
Total research and development revenue     742   1,065 22,220 2,218      
Total collaboration revenue     9,408   1,065 50,070 2,218      
Operating expenses:                    
Research and Development Expense     274   444 703 973      
General and Administrative Expense     38   84 149 315      
Total Operating expenses     312   528 $ 852 1,288      
Percentage of royalty based on contractually defined profits on sales           50.00%        
Profits recorded on sales     8,700     $ 36,900        
Number of shares sold | shares   4,708,679                
Per share price of shares sold | $ / shares   $ 15.93                
Closing price of the company's common stock on the NASDAQ Global Market (in dollars per share) | $ / shares   $ 13.05                
Aggregate purchase price of shares sold   $ 75,000                
Premium paid   $ 13,600                
Collaborative Arrangement, Legal Expenses           9,000        
Second Sandoz Collaboration Agreement | Maximum                    
Operating expenses:                    
Milestone payments possible per agreement     143,000     143,000        
Commercial milestone payments     10,000     10,000        
Sales-based and commercial milestone payments possible per agreement     120,000     120,000        
Sales-based and commercial milestone payments possible in European Union           23,000        
Regulatory milestone payment earned           $ 10,000        
Second Sandoz Collaboration Agreement | Novartis Pharma AG                    
Operating expenses:                    
Percentage of contractual profits earned under collaborative arrangement           50.00%        
Baxalta Agreement                    
Research and development revenue                    
Amortization of upfront payments     2,442   767 $ 6,572 2,309      
Research and development services (FTEs) and external costs     1,876   2,595 7,323 10,532      
Total research and development revenue     4,318   3,362 13,895 12,841      
Total collaboration revenue     4,318   3,362 13,895 12,841      
Operating expenses:                    
Research and Development Expense     251   3,639 1,376 11,868      
General and Administrative Expense     166   242 798 399      
Total Operating expenses     417   $ 3,881 $ 2,174 $ 12,267      
Number of independent companies completed restructuring activities | item           2        
Number of additional biosimilars under the agreement | item           4        
Upfront payment paid by Baxter to the company           $ 33,000        
Option payments agreed to be paid by Baxter with respect to additional product candidates           12,000        
Option payment which the entity is no longer eligible to receive           7,000        
Remaining payment obligation     $ 0     $ 0        
Baxalta Agreement | Accounting Standards Update 2009 to 2013 Member                    
Operating expenses:                    
Number of significant deliverables identified in arrangement | item           7        
Total arrangement consideration           $ 61,000        
Portion of revised arrangement consideration reallocated to the remaining deliverables $ 40,000                  
Portion of revised arrangement consideration allocated to the first initial product license as a result of termination of product 39,600                  
Portion of revised arrangement consideration allocated to each of the three additional product licenses as a result of termination of product $ 400                  
Decrease in portion of revised arrangement consideration reallocated to the remaining deliverables           $ 40,000        
Estimate performance period for the joint steering committee           6 years        
Number of follow-on biologic products for development and product licenses | item           2        
Number of additional follow-on biologic products for development and product licenses | item           4        
Number of additional follow-on biologic products for research and development services | item           4        
Deferred revenue           $ 24,400        
Deferred revenue included in current liabilities           9,800        
Deferred revenue included in non-current liabilities           14,600        
Baxalta Agreement | Maximum                    
Operating expenses:                    
Aggregate regulatory milestone to be paid by Baxter           $ (50,000)