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Collaboration and License Agreements (Details)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended 15 Months Ended 33 Months Ended
Feb. 28, 2015
USD ($)
Oct. 31, 2014
USD ($)
Jul. 31, 2006
USD ($)
$ / shares
shares
Jun. 30, 2015
USD ($)
Jun. 30, 2014
USD ($)
Jun. 30, 2015
USD ($)
item
Jun. 30, 2014
USD ($)
Jun. 30, 2015
USD ($)
Jun. 30, 2014
USD ($)
Dec. 31, 2013
USD ($)
Sep. 30, 2011
Mar. 31, 2015
Collaboration revenues:                        
Product revenue       $ 19,305,000 $ 5,690,000 $ 22,027,000 $ 10,502,000          
Research and development revenue                        
Regulatory and commercial milestones       20,000,000   20,000,000            
Amortization of upfront payments       2,442,000 860,000 4,130,000 1,901,000          
Research and development services and external costs       3,153,000 4,400,000 7,306,000 9,332,000          
Total research and development revenue       25,595,000 5,260,000 31,436,000 11,233,000          
Total collaboration revenue       44,900,000 10,950,000 53,463,000 21,735,000          
Operating expenses:                        
Research and Development Expense       976,000 3,708,000 1,762,000 8,841,000          
General and Administrative Expense       372,000 300,000 965,000 483,000          
Total Operating expenses       1,348,000 4,008,000 2,727,000 9,324,000          
2003 Sandoz Collaboration                        
Collaboration revenues:                        
Product revenue       121,000 5,690,000 2,843,000 10,502,000          
Research and development revenue                        
Research and development services and external costs       130,000 278,000 381,000 602,000          
Total research and development revenue       130,000 278,000 381,000 602,000          
Total collaboration revenue       251,000 5,968,000 3,224,000 11,104,000          
Operating expenses:                        
Research and Development Expense       177,000 64,000 208,000 83,000          
General and Administrative Expense       112,000 86,000 222,000 95,000          
Total Operating expenses       289,000 150,000 $ 430,000 178,000          
Percentage of contractual profits earned under collaborative arrangement                     45.00%  
Percentage of royalty for net sales up to pre-defined sales threshold                       10.00%
Percentage of royalty for net sales above pre-defined sales threshold                       12.00%
Percentage of royalty based on contractually defined profits on sales           50.00%            
Profits recorded on sales       100,000                
Claw-back adjustment of pre-launch development expenses       100,000                
Maximum percentage of reduction of profit-share, royalty and milestone payments from Sandoz at each quarter           50.00%            
Reduction in product revenue due to netting of shared development and other expenses               $ 1,900,000 $ 2,200,000      
Collaborative Arrangement, carry forward to future periods           $ 1,800,000            
Decrease in amount of adjustment related to product revenue           $ 2,100,000            
Number of significant deliverables identified in arrangement | item           2            
Second Sandoz Collaboration Agreement                        
Collaboration revenues:                        
Product revenue       19,184,000   $ 19,184,000            
Research and development revenue                        
Regulatory and commercial milestones       20,000,000   20,000,000            
Amortization of upfront payments         120,000   359,000          
Research and development services and external costs       794,000 604,000 1,478,000 794,000          
Total research and development revenue       20,794,000 724,000 21,478,000 1,153,000          
Total collaboration revenue       39,978,000 724,000 40,662,000 1,153,000          
Operating expenses:                        
Research and Development Expense       282,000 232,000 429,000 529,000          
General and Administrative Expense       33,000 88,000 110,000 231,000          
Total Operating expenses       315,000 320,000 $ 539,000 760,000          
Percentage of royalty based on contractually defined profits on sales           50.00%            
Profits recorded on sales       28,200,000                
Number of shares sold | shares     4,708,679                  
Per share price of shares sold | $ / shares     $ 15.93                  
Closing price of the company's common stock on the NASDAQ Global Market (in dollars per share) | $ / shares     $ 13.05                  
Aggregate purchase price of shares sold     $ 75,000,000                  
Premium paid     $ 13,600,000                  
Collaborative Arrangement, Legal Expenses       9,000,000                
Second Sandoz Collaboration Agreement | Maximum                        
Operating expenses:                        
Milestone payments possible per agreement       143,000,000   $ 143,000,000   143,000,000        
Commercial milestone payments       10,000,000   10,000,000   10,000,000        
Sales-based and commercial milestone payments possible per agreement       120,000,000   120,000,000   120,000,000        
Sales-based and commercial milestone payments possible in European Union           $ 23,000,000            
Regulatory milestone payment earned       10,000,000                
Second Sandoz Collaboration Agreement | Novartis Pharma AG                        
Operating expenses:                        
Percentage of contractual profits earned under collaborative arrangement           50.00%            
Baxalta Agreement                        
Research and development revenue                        
Amortization of upfront payments       2,442,000 740,000 $ 4,130,000 1,542,000          
Research and development services and external costs       2,229,000 3,518,000 5,447,000 7,936,000          
Total research and development revenue       4,671,000 4,258,000 9,577,000 9,478,000          
Total collaboration revenue       4,671,000 4,258,000 9,577,000 9,478,000          
Operating expenses:                        
Research and Development Expense       517,000 3,412,000 1,125,000 8,229,000          
General and Administrative Expense       227,000 126,000 633,000 157,000          
Total Operating expenses       744,000 $ 3,538,000 $ 1,758,000 $ 8,386,000          
Number of independent companies completed restructuring activities | item           2            
Number of additional biosimilars under the agreement | item           4            
Upfront payment paid by Baxter to the company           $ 33,000,000            
Option payments agreed to be paid by Baxter with respect to additional product candidates           12,000,000            
Option payment which the entity is no longer eligible to receive           7,000,000            
Remaining payment obligation       $ 0   $ 0   $ 0        
Baxalta Agreement | Accounting Standards Update 2009 to 2013 Member                        
Operating expenses:                        
Number of significant deliverables identified in arrangement | item           7            
Current number of significant deliverables identified in arrangement | item           6            
Total arrangement consideration           $ 61,000,000            
Portion of arrangement consideration allocated to the first initial product license           10,300,000            
Portion of arrangement consideration allocated to each of the four additional product licenses           10,300,000            
Portion of arrangement consideration allocated to the second initial product license           9,400,000            
Portion of arrangement consideration allocated to the joint steering committee unit of accounting           $ 114,000            
Reduction in total arrangement consideration   $ 7,000,000               $ 7,000,000    
Reduction in number of significant deliverables identified in arrangement | item           1            
Portion of revised arrangement consideration reallocated to the remaining deliverables $ 40,000,000 61,000,000               54,000,000    
Portion of revised arrangement consideration allocated to the first initial product license as a result of termination of product 39,600,000 12,400,000               11,000,000    
Portion of revised arrangement consideration allocated to each of the three additional product licenses as a result of termination of product $ 400,000 12,400,000               11,000,000    
Portion of revised arrangement consideration allocated to the second initial product license as a result of termination of product   11,300,000               10,000,000    
Portion of revised arrangement consideration allocated to the joint steering committee unit of accounting as a result of termination of product   $ 137,000               $ 122,000    
Decrease in portion of revised arrangement consideration reallocated to the remaining deliverables           $ 40,000,000            
Number of follow-on biologic products for development and product licenses | item           2            
Number of additional follow-on biologic products for development and product licenses | item           4            
Number of follow-on biologic products for research and development services | item           2            
Number of additional follow-on biologic products for research and development services | item           4            
Number of vendors selling similar, competing products on a stand-alone basis | item           0            
Number of license agreements | item           6            
Deferred revenue           $ 26,900,000            
Deferred revenue included in current liabilities           9,800,000            
Deferred revenue included in non-current liabilities           17,100,000            
Baxalta Agreement | Maximum                        
Operating expenses:                        
Aggregate regulatory milestone to be paid by Baxter           $ (50,000,000)