CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2013	Mar. 31, 2012
Collaboration revenues:
Product revenue	$ 5,396	$ 22,029
Research and development revenue	2,207	2,199
Total collaboration revenue	7,603	24,228
Operating expenses:
Research and development	22,332	18,562
General and administrative	9,716	10,955
Total operating expenses	32,048	29,517
Operating loss	(24,445)	(5,289)
Other income (expense):
Interest income	269	307
Other income	60
Total other income	329	307
Net loss	(24,116)	(4,982)
Basic and diluted net loss per share (in dollar per share)	$ (0.48)	$ (0.10)
Shares used in computing basic and diluted net loss per share (in shares)	50,635	50,240
Comprehensive loss	$ (24,181)	$ (4,875)