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Summary of Significant Accounting Policies (Details 2) (USD $)
3 Months Ended
Mar. 31, 2013
Mar. 31, 2013
Recurring
Fair value
Dec. 31, 2012
Recurring
Fair value
Mar. 31, 2013
Recurring
Fair value
Cash and cash equivalents
Dec. 31, 2012
Recurring
Fair value
Cash and cash equivalents
Mar. 31, 2013
Recurring
Fair value
U.S. Government-sponsored enterprise obligations
Dec. 31, 2012
Recurring
Fair value
U.S. Government-sponsored enterprise obligations
Mar. 31, 2013
Recurring
Fair value
Corporate debt securities
Dec. 31, 2012
Recurring
Fair value
Corporate debt securities
Mar. 31, 2013
Recurring
Fair value
Commercial paper obligations
Dec. 31, 2012
Recurring
Fair value
Commercial paper obligations
Mar. 31, 2013
Recurring
Fair value
Foreign government bonds
Dec. 31, 2012
Recurring
Fair value
Foreign government bonds
Mar. 31, 2013
Recurring
Quoted Prices in Active Markets (Level 1)
Dec. 31, 2012
Recurring
Quoted Prices in Active Markets (Level 1)
Mar. 31, 2013
Recurring
Quoted Prices in Active Markets (Level 1)
Cash and cash equivalents
Dec. 31, 2012
Recurring
Quoted Prices in Active Markets (Level 1)
Cash and cash equivalents
Mar. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Dec. 31, 2012
Recurring
Significant Other Observable Inputs (Level 2)
Mar. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
U.S. Government-sponsored enterprise obligations
Dec. 31, 2012
Recurring
Significant Other Observable Inputs (Level 2)
U.S. Government-sponsored enterprise obligations
Mar. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Corporate debt securities
Dec. 31, 2012
Recurring
Significant Other Observable Inputs (Level 2)
Corporate debt securities
Mar. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Commercial paper obligations
Dec. 31, 2012
Recurring
Significant Other Observable Inputs (Level 2)
Commercial paper obligations
Mar. 31, 2013
Recurring
Significant Other Observable Inputs (Level 2)
Foreign government bonds
Dec. 31, 2012
Recurring
Significant Other Observable Inputs (Level 2)
Foreign government bonds
Fair Value Measurements                                                      
Assets fair value   $ 319,764,000 $ 335,553,000 $ 38,848,000 $ 47,940,000 $ 67,788,000 $ 51,225,000 $ 145,526,000 $ 158,913,000 $ 57,633,000 $ 65,138,000 $ 9,969,000 $ 12,337,000 $ 38,848,000 $ 47,940,000 $ 38,848,000 $ 47,940,000 $ 280,916,000 $ 287,613,000 $ 67,788,000 $ 51,225,000 $ 145,526,000 $ 158,913,000 $ 57,633,000 $ 65,138,000 $ 9,969,000 $ 12,337,000
Transfer from Level 1 to Level 2, assets 0                                                    
Transfer from Level 2 to Level 1, assets 0                                                    
Other-than-temporary impairment $ 0