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CONDENSED STATEMENT OF STOCKHOLDERS' EQUITY (DEFICIT) - USD ($)
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive Income (Loss)
Retained Deficit
Total
Balance at beginning of period at Dec. 31, 2016     $ (41,196)    
Net loss         $ (46,500,131)
Unrealized gain on securities         36,636
Balance at end of period at Sep. 30, 2017     (4,560)    
Balance at beginning of period at Jun. 30, 2017     (34,863)    
Net loss         (23,266,818)
Unrealized gain on securities         30,303
Balance at end of period at Sep. 30, 2017     (4,560)    
Cumulative effect of adoption of ASC 606 | ASU 2014-09       $ 339,406 339,406
Balance after adjustment $ 48,204 $ 404,454,909 (64,433) (308,615,129) 95,823,551
Balance at beginning of period at Dec. 31, 2017 $ 48,204 404,454,909 (64,433) (308,954,535) 95,484,145
Balances (in shares) at Dec. 31, 2017 48,203,529        
Exercise of stock options $ 1,517 9,837,268     9,838,785
Exercise of stock options (in shares) 1,516,796        
Issuance of common stock in connection with equity offering $ 31,414 269,794,204     269,825,618
Issuance of common stock in connection with equity offering (in shares) 31,414,093        
Stock-based compensation $ 163 4,346,471     4,346,634
Stock-based compensation (in shares) 163,530        
Employee stock purchase plan $ 25 95,045     95,070
Employee stock purchase plan (in shares) 25,352        
Net loss       (32,774,814) (32,774,814)
Unrealized gain on securities     41,749   41,749
Balance at end of period at Sep. 30, 2018 $ 81,323 688,527,897 (22,684) (341,389,943) $ 347,196,593
Balances (in shares) at Sep. 30, 2018 81,323,300        
Balance at beginning of period at Jun. 30, 2018     (34,324)    
Exercise of stock options (in shares)         442,913
Net loss         $ (12,607,525)
Unrealized gain on securities         11,640
Balance at end of period at Sep. 30, 2018 $ 81,323 $ 688,527,897 $ (22,684) $ (341,389,943) $ 347,196,593
Balances (in shares) at Sep. 30, 2018 81,323,300