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Collaborations and Other Arrangements - ABX (Details)
$ in Millions
1 Months Ended 3 Months Ended
Sep. 29, 2017
USD ($)
item
shares
Oct. 31, 2017
person
item
Jun. 30, 2018
item
ABX Development and License Agreement      
Number of patients with mCRPC included in study | item     750
ABX | License Agreement      
ABX Development and License Agreement      
Upfront cash payment $ 11.9    
Total consideration excluding common stock shares and warrants $ 12.0    
Issuance of common stock in connection with development and license agreement (in shares) | shares 2,000,000    
Number of warrants issued per agreement | item 2    
Aggregate number of common stock shares that may be purchased by exercise of warrants | shares 4,000,000    
ABX | Maximum | License Agreement      
ABX Development and License Agreement      
Aggregate number of common stock shares that may be purchased by exercise of warrants | shares 4,000,000    
ABX | Achievement Of Regulatory Milestones | License Agreement      
ABX Development and License Agreement      
Potential milestone payments to be paid $ 25.0    
ABX | Achievement Of Sales Milestones | License Agreement      
ABX Development and License Agreement      
Potential milestone payments to be paid $ 135.0    
University of Sydney | Anzup | Three Party Agreement [Member]      
ABX Development and License Agreement      
Number of parties in the agreement | item   3  
Number of patients with mCRPC included in study | person   200