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Collaborations and Other Arrangements - ABX (Details)
$ in Millions
1 Months Ended 3 Months Ended
Sep. 29, 2017
USD ($)
item
shares
Oct. 31, 2017
person
Sep. 30, 2017
person
Mar. 31, 2018
item
ABX Development and License Agreement        
Number of patients with mCRPC included in study | person     750  
ABX | License Agreement        
ABX Development and License Agreement        
Upfront cash payment $ 11.9      
Total consideration excluding common stock shares and warrants $ 12.0      
Issuance of common stock in connection with development and license agreement (in shares) | shares 2,000,000      
Number of warrants issued per agreement | item 2      
Aggregate number of common stock shares that may be purchased by exercise of warrants | shares 4,000,000      
ABX | Maximum | License Agreement        
ABX Development and License Agreement        
Aggregate number of common stock shares that may be purchased by exercise of warrants | shares 4,000,000      
ABX | Achievement Of Regulatory Milestones | License Agreement        
ABX Development and License Agreement        
Potential milestone payments to be paid $ 25.0      
ABX | Achievement Of Sales Milestones | License Agreement        
ABX Development and License Agreement        
Potential milestone payments to be paid $ 135.0      
University of Sydney | Anzup | Three Party Agreement [Member]        
ABX Development and License Agreement        
Number of parties in the agreement | item       3
Number of patients with mCRPC included in study | person   200