Restructuring Costs (Tables)

9 Months Ended

Sep. 30, 2017

Restructuring Costs [Abstract]

Schedule of restructuring and related costs

The following tables summarize the restructuring accruals for the three and nine months ended September 30, 2017.

			EC1456
	Employee		Phase 1b Trial		Other
	Termination		Termination		Restructuring
	Accrual		Accrual		Costs Accrual		Total
Balance, June 30, 2017	$	181,500	$	778,100	$	45,100	$	1,004,700
Charges for the three months ended September 30, 2017		—		—		—		—
Amounts paid in the three months ended September 30, 2017		(181,500)		(409,764)		(7,500)		(598,764)
Balance, September 30, 2017	$	—	$	368,336	$	37,600	$	405,936

			EC1456
	Employee		Phase 1b Trial		Other
	Termination		Termination		Restructuring
	Accrual		Accrual		Costs Accrual		Total
Balance, January 1, 2017	$	—	$	—	$	—	$	—
Charges for the nine months ended September 30, 2017		1,029,400		947,100		126,500		2,103,000
Amounts paid in the nine months ended September 30, 2017		(1,029,400)		(578,764)		(88,900)		(1,697,064)
Balance, September 30, 2017	$	—	$	368,336	$	37,600	$	405,936