Restructuring Costs (Tables)

9 Months Ended

Sep. 30, 2016

Restructuring Costs [Abstract]

Restructuring and Related Costs [Table Text Block]

	PROCEED
	Trial
	Termination
	Accrual
Balance at June 30, 2016	$	23,600
Amounts paid in the three months ended September 30, 2016		(5,800)
Balance, September 30, 2016	$	17,800

	PROCEED
	Trial
	Termination
	Accrual
Balance, December 31, 2015	$	46,600
Amounts paid in the nine months ended September 30, 2016		(28,800)
Balance, September 30, 2016	$	17,800