X0306 4 2020-06-16 0 0001501756 Adverum Biotechnologies, Inc. ADVM 0001233539 PATTERSON LEONE D C/O ADVERUM BIOTECHNOLOGIES, INC. 800 SAGINAW DRIVE REDWOOD CITY CA 94063 0 1 0 0 President Common Stock 2020-06-16 4 S 0 13171 24.68 D 110488 D The shares were sold pursuant to an irrevocable election previously made by the Reporting Person to sell shares of common stock necessary to cover the federal, state and local tax withholding obligations, as well as related brokerage commission fees. Leone Patterson by /s/ Peter Soparkar, Attorney-in-Fact. 2020-06-17