X0201 3 2003-11-05 0 0000927829 NITROMED INC NTMD 0001233414 LOBERG MICHAEL D C/O NITROMED, INC. 12 OAK PARK DRIVE BEDFORD MA 01730 1 1 0 0 President & CEO Common Stock 286608 D Incentive Stock Option (right to buy) 0.72 2003-11-05 2008-01-26 Common Stock 161500 D Incentive Stock Option (right to buy) 1.30 2003-11-05 2009-06-16 Common Stock 6700 D Incentive Stock Option (right to buy) 1.30 2009-06-16 Common Stock 26800 D Incentive Stock Option (right to buy) 2.00 2011-01-30 Common Stock 60000 D Incentive Stock Option (right to buy) 2.00 2013-06-17 Common Stock 100000 D 10% of the options vested and became exercisable on June 16, 2000 and the remainder vests and becomes exercisable in four equal annual installments beginning June 16, 2001. The option vests and becomes exercisable in four equal annual installments on each of January 30, 2002, 2003, 2004 and 2005. The option vests and becomes exercisable in four equal annual installments on each of January 17, 2003, 2004, 2005 and 2006. /s/ Michael D. Loberg 2003-11-05