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    <nameOfIssuer>908 DEVICES INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
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    <nameOfIssuer>ACADIA PHARMACEUTICALS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
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    <nameOfIssuer>ACELRX PHARMACEUTICALS INC</nameOfIssuer>
    <titleOfClass>COM NEW</titleOfClass>
    <cusip>00444T209</cusip>
    <value>113100</value>
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    <titleOfClass>SPONDS ADR</titleOfClass>
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    <cusip>007002108</cusip>
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    <nameOfIssuer>ADMA BIOLOGICS INC</nameOfIssuer>
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    <nameOfIssuer>ALIGOS THERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>01626L105</cusip>
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    <nameOfIssuer>AMARIN CORP PLC</nameOfIssuer>
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    <cusip>023111206</cusip>
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    <nameOfIssuer>ARS PHARMACEUTICALS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>82835W108</cusip>
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    <cusip>04335A105</cusip>
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    <nameOfIssuer>ASCENDIS PHARMA A/S</nameOfIssuer>
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    <cusip>04351P101</cusip>
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    <nameOfIssuer>ASLAN PHARMACEUTICALS LTD</nameOfIssuer>
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    <cusip>046353108</cusip>
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    <titleOfClass>COM</titleOfClass>
    <cusip>04683R106</cusip>
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    <nameOfIssuer>AURINIA PHARMACEUTICALS INC</nameOfIssuer>
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    <cusip>05156V102</cusip>
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    <cusip>05337M104</cusip>
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    <titleOfClass>COM</titleOfClass>
    <cusip>05455M100</cusip>
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    <titleOfClass>COM</titleOfClass>
    <cusip>05464T104</cusip>
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    <nameOfIssuer>BANK HAWAII CORP</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
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    <cusip>07725L102</cusip>
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    <nameOfIssuer>BIO RAD LABS INC</nameOfIssuer>
    <titleOfClass>CL A</titleOfClass>
    <cusip>090572207</cusip>
    <value>8602800</value>
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    <titleOfClass>COM</titleOfClass>
    <cusip>09077B104</cusip>
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    <titleOfClass>COM</titleOfClass>
    <cusip>09058V103</cusip>
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    <titleOfClass>COM</titleOfClass>
    <cusip>G1110E107</cusip>
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    <nameOfIssuer>BIONOMICS LIMITED</nameOfIssuer>
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    <cusip>09063M205</cusip>
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    <nameOfIssuer>BLACK DIAMOND THERAPEUTICS I</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>09203E105</cusip>
    <value>1148000</value>
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    <nameOfIssuer>BLUEBIRD BIO INC</nameOfIssuer>
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    <value>13019794</value>
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    <nameOfIssuer>BOLT BIOTHERAPEUTICS INC</nameOfIssuer>
    <titleOfClass>COM</titleOfClass>
    <cusip>097702104</cusip>
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    <nameOfIssuer>CITIGROUP INC</nameOfIssuer>
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    <titleOfClass>COM</titleOfClass>
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    <titleOfClass>COM</titleOfClass>
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</informationTable>
