X0306 4 2021-11-29 0 0000920465 LA JOLLA PHARMACEUTICAL CO LJPC 0001178579 TANG KEVIN C 4747 EXECUTIVE DRIVE, SUITE 210 SAN DIEGO CA 92121 1 0 1 0 0001191935 TANG CAPITAL PARTNERS LP 4747 EXECUTIVE DRIVE, SUITE 210 SAN DIEGO CA 92121 0 0 1 0 0001232621 TANG CAPITAL MANAGEMENT LLC 4747 EXECUTIVE DRIVE, SUITE 210 SAN DIEGO CA 92121 0 0 1 0 0001759910 Hearne Michael S 4747 EXECUTIVE DRIVE, SUITE 210 SAN DIEGO CA 92121 0 1 0 0 Chief Financial Officer Common Stock 2021-11-29 4 S 0 193403 4.1008 D 9855821 I By LP Common Stock 2021-11-30 4 S 0 6597 3.9514 D 9849224 I By LP Common Stock 2021-11-30 4 S 0 63745 3.9461 D 9785479 I By LP Common Stock 2021-12-01 4 S 0 136255 3.7586 D 9649224 I By LP Common Stock 2021-12-01 4 S 0 41290 3.6644 D 9607934 I By LP The Reporting Person has delivered to the Issuer the full amount of the disgorgeable profit arising the sale reported herein, in the amount of $4,380.25. The prices reported in Column 4 are weighted-average prices. These shares were sold in multiple transactions at prices ranging from $3.90 to $4.74. The Reporting Persons undertake to provide the Issuer, any security holder of the Issuer or the SEC Staff, upon request, full information regarding the number of shares sold at each price within the ranges set forth in footnotes 2 and 4 through 7 herein. The shares are beneficially owned by Tang Capital Partners, LP ("TCP"). Kevin Tang is the sole manager of Tang Capital Management, LLC ("TCM"), which is the general partner of TCP. Michael Hearne is the Chief Financial Officer of La Jolla Pharmaceutical Company, as well as Chief Financial Officer of TCM. Mr. Tang and Mr. Hearne each have a pecuniary interest in the shares beneficially held by TCP. The prices reported in Column 4 are weighted-average prices. These shares were sold in multiple transactions at prices ranging from $3.95 to $3.96. The prices reported in Column 4 are weighted-average prices. These shares were sold in multiple transactions at prices ranging from $3.90 to $4.051. The prices reported in Column 4 are weighted-average prices. These shares were sold in multiple transactions at prices ranging from $3.70 to $3.89. The prices reported in Column 4 are weighted-average prices. These shares were sold in multiple transactions at prices ranging from $3.60 to $3.75 /s/ Kevin Tang 2021-12-01 /s/ Kevin Tang, Managing Member of Tang Capital Management, LLC, General Partner 2021-12-01 /s/ Kevin Tang, Managing Member 2021-12-01 /s/ Michael Hearne 2021-12-01