X0306 4 2021-11-23 1 0001671584 Aptevo Therapeutics Inc. APVO 0001178579 TANG KEVIN C 4747 EXECUTIVE DRIVE SUITE 210 SAN DIEGO CA 92121 0 0 0 1 Exit Filing 0001232621 TANG CAPITAL MANAGEMENT LLC 4747 EXECUTIVE DRIVE SUITE 210 SAN DIEGO CA 92121 0 0 0 1 Exit Filing 0001191935 TANG CAPITAL PARTNERS LP 4747 EXECUTIVE DRIVE SUITE 210 SAN DIEGO CA 92121 0 0 0 1 Exit Filing Common Stock 2021-11-23 4 S 0 161336 13.5216 D 760000 I By LP Common Stock 2021-11-23 4 S 0 124509 12.4504 D 635491 I By LP Common Stock 2021-11-23 4 S 0 75491 11.7422 D 560000 I By LP Common Stock 2021-11-23 4 S 0 149111 11.1892 D 410889 I By LP Common Stock 2021-11-23 4 S 0 50889 10.4279 D 360000 I By LP Common Stock 2021-11-23 4 S 0 200000 10.0722 D 160000 I By LP Common Stock 2021-11-23 4 S 0 160000 9.6035 D 0 I By LP The prices reported in Column 4 are weighted average prices. These shares were sold in multiple transactions at prices ranging from $13.29 to $13.77. The Reporting Persons undertake to provide the Issuer, any security holder of the Issuer or the SEC Staff, upon request, full information regarding the number of shares sold at each price within the ranges set forth in footnotes 1 and 3 through 8 herein. The shares are beneficially owned by Tang Capital Partners, LP ("TCP"). Kevin Tang is the sole manager of Tang Capital Management, LLC ("TCM"), which is the general partner of TCP. Mr. Tang has a pecuniary interest in a portion of the shares beneficially held by TCP. The prices reported in Column 4 are weighted-average prices. These shares were sold in multiple transactions at prices ranging from $11.97 to $12.90. The prices reported in Column 4 are weighted-average prices. These shares were sold in multiple transactions at prices ranging from $11.59 to $11.89. The prices reported in Column 4 are weighted-average prices. These shares were sold in multiple transactions at prices ranging from $10.74 to $11.67. The prices reported in Column 4 are weighted-average prices. These shares were sold in multiple transactions at prices ranging from $10.31 to $10.64. The prices reported in Column 4 are weighted-average prices. These shares were sold in multiple transactions at prices ranging from $9.59 to $10.34. The prices reported in Column 4 are weighted-average prices. These shares were sold in multiple transactions at prices ranging from $9.50 to $10.20. /s/ Kevin Tang 2021-11-26 /s/ Kevin Tang, Managing Member 2021-11-26 /s/ Kevin Tang, Managing Member of Tang Capital Management, LLC, General Partner 2021-11-26