X0306 5 2012-12-31 0 0 0 0000818033 AP PHARMA INC /DE/ APPA 0001178579 TANG KEVIN C 4747 EXECUTIVE DRIVE SUITE 510 SAN DIEGO CA 92121 1 0 1 0 0001232621 TANG CAPITAL MANAGEMENT LLC 4747 EXECUTIVE DRIVE SUITE 510 SAN DIEGO CA 92121 0 0 1 0 0001191935 TANG CAPITAL PARTNERS LP 4747 EXECUTIVE DRIVE SUITE 510 SAN DIEGO CA 92121 0 0 1 0 Common Stock 2012-12-19 5 G 0 5746716 0.00 D 64213600 I By LP Common Stock 286950 I As Trustee Common Stock 138841 D The gifted securities were held by Kevin C. Tang, in his capacity as Trustee of the Tang Family Trust, and such shares were donated to a charitable foundation that Mr. Tang controls. Accordingly, Mr. Tang continues to exercise voting and dispositive powers over the securities owned by such foundation, although he disclaims any pecuniary interest in such shares. Prior to the reported gift, such securities were distributed to the Tang Family Trust from Tang Capital Partners, LP, which was the record and beneficial holder of the shares. The securities are held by Tang Capital Partners, LP. Kevin C. Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of Tang Capital Partners, LP. Mr. Tang disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein. The securities are owned by Kevin C. Tang as custodian for his minor children, as Trustee of the Tang Family Trust and as Trustee of the Tang Advisors, LLC Profit Sharing Plan, for which Mr. Tang serves as Trustee and in which he is a participant. Mr. Tang disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein. 42,950 of these securities are held by Kevin C. Tang's IRA. /s/ Kevin C. Tang 2013-02-14 /s/ Kevin C. Tang, Managing Member 2013-02-14 /s/ Kevin C. Tang, Managing Member of Tang Capital Management, LLC, General Partner 2013-02-14