X0303 4 2010-01-11 0 0001347178 Vanda Pharmaceuticals Inc. VNDA 0001178579 TANG KEVIN C 4401 EASTGATE MALL SAN DIEGO CA 92121 0 0 1 0 0001232621 TANG CAPITAL MANAGEMENT LLC 4401 EASTGATE MALL SAN DIEGO CA 92121 0 0 1 0 0001191935 TANG CAPITAL PARTNERS LP 4401 EASTGATE MALL SAN DIEGO CA 92121 0 0 1 0 Common Stock 2010-01-11 4 S 0 35681 11.0042 D 2884671 I By LP Common Stock 2010-01-12 4 S 0 27419 10.8797 D 2857252 I By LP Common Stock 2010-01-13 4 S 0 86500 10.5441 D 2770752 I By LP The securities are held by Tang Capital Partners, LP. Kevin C. Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of Tang Capital Partners, LP. Mr. Tang disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. /s/ Kevin C. Tang 2010-01-13 /s/ Kevin C. Tang, Managing Member 2010-01-13 /s/ Kevin C. Tang, as Managing Member of Tang Capital Management, LLC, General Partner 2010-01-13