X0202 4 2007-06-11 0 0001103390 Ardea Biosciences, Inc./DE ARDC 0001178579 TANG KEVIN C 4401 EASTGATE MALL SAN DIEGO CA 92121 1 0 1 0 0001232621 TANG CAPITAL MANAGEMENT LLC 4401 EASTGATE MALL SAN DIEGO CA 92121 0 0 1 0 0001191935 TANG CAPITAL PARTNERS LP 4401 EASTGATE MALL SAN DIEGO CA 92121 0 0 1 0 Common Stock 2007-06-11 4 X 0 426154 1.033 A 2144896 I By LP Common Stock 196294 I As Trustee Common Stock 15089 D Common Stock Warrant (Right to Buy) 1.033 2007-06-11 4 X 0 426154 0.00 D 2003-05-01 2008-05-01 Common Stock 426154 0 I By LP Includes 7,890 shares and 6,291 shares issued to Tang Capital Partners, LP as dividends on shares of the issuer's Series A Convertible Preferred Stock on 12/31/06 and 3/31/07, respectively. The securities are held by Tang Capital Partners, LP. Kevin C. Tang is the sole manager of Tang Capital Management, LLC, which is the general partner of Tang Capital Partners, LP. Mr. Tang disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. The securities are owned by Kevin C. Tang as custodian for his minor children, as Trustee of the Tang Family Trust and as Trustee of the Tang Advisors, LLC Profit Sharing Plan, for which Mr. Tang serves as Trustee and in which he is a participant. Mr. Tang disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein. The securities are owned by Kevin C. Tang's IRA. /s/ Kevin C. Tang 2007-06-13 Kevin C. Tang, Managing Member 2007-06-13 Kevin C. Tang, as Managing Member of Tang Capital Management, LLC, General Partner 2007-06-13