<?xml version="1.0"?>
<ownershipDocument>
    <schemaVersion>X0201</schemaVersion>

    <documentType>4</documentType><periodOfReport>2003-10-06</periodOfReport>
    <issuer>
        <issuerCik>0001103390</issuerCik>
        <issuerName>INTRABIOTICS PHARMACEUTICALS INC /DE</issuerName>
        <issuerTradingSymbol>IBPI</issuerTradingSymbol></issuer><reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001178579</rptOwnerCik>
            <rptOwnerName>TANG KEVIN C</rptOwnerName>
        </reportingOwnerId>
<reportingOwnerAddress><rptOwnerStreet1>4401 Eastgate Mall</rptOwnerStreet1><rptOwnerStreet2/><rptOwnerCity>San Diego</rptOwnerCity><rptOwnerState>CA</rptOwnerState><rptOwnerZipCode>92121</rptOwnerZipCode></reportingOwnerAddress><reportingOwnerRelationship><isDirector>1</isDirector><isOfficer>0</isOfficer><isTenPercentOwner>1</isTenPercentOwner><isOther>0</isOther></reportingOwnerRelationship></reportingOwner><reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001191935</rptOwnerCik>
            <rptOwnerName>TANG CAPITAL PARTNERS LP</rptOwnerName>
        </reportingOwnerId>
<reportingOwnerAddress><rptOwnerStreet1>4401 Eastgate Mall</rptOwnerStreet1><rptOwnerStreet2/><rptOwnerCity>San Diego</rptOwnerCity><rptOwnerState>CA</rptOwnerState><rptOwnerZipCode>92121</rptOwnerZipCode></reportingOwnerAddress><reportingOwnerRelationship><isDirector>0</isDirector><isOfficer>0</isOfficer><isTenPercentOwner>1</isTenPercentOwner><isOther>0</isOther></reportingOwnerRelationship></reportingOwner><reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001232621</rptOwnerCik>
            <rptOwnerName>TANG CAPITAL MANAGEMENT LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>4401 EASTGATE MALL</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>SAN DIEGO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92121</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
            <reportingOwnerRelationship>
<isDirector>0</isDirector><isOfficer>0</isOfficer><isTenPercentOwner>1</isTenPercentOwner><isOther>0</isOther></reportingOwnerRelationship></reportingOwner><nonDerivativeTable><nonDerivativeTransaction><securityTitle><value>Common Stock</value></securityTitle><transactionDate><value>2003-10-06</value></transactionDate><transactionCoding><transactionFormType>4</transactionFormType><transactionCode>P</transactionCode><equitySwapInvolved>0</equitySwapInvolved></transactionCoding><transactionAmounts><transactionShares><value>120000</value></transactionShares><transactionPricePerShare><value>10.85</value></transactionPricePerShare><transactionAcquiredDisposedCode><value>A</value></transactionAcquiredDisposedCode></transactionAmounts><postTransactionAmounts><sharesOwnedFollowingTransaction><value>323633</value><footnoteId id="F2"/></sharesOwnedFollowingTransaction></postTransactionAmounts><ownershipNature><directOrIndirectOwnership><value>I</value></directOrIndirectOwnership><natureOfOwnership><value>See Note</value><footnoteId id="F1"/></natureOfOwnership></ownershipNature></nonDerivativeTransaction></nonDerivativeTable><derivativeTable><derivativeTransaction><securityTitle><value>Common Stock Warrant (right to buy)</value></securityTitle><conversionOrExercisePrice><value>10.85</value></conversionOrExercisePrice><transactionDate><value>2003-10-06</value></transactionDate><transactionCoding><transactionFormType>4</transactionFormType><transactionCode>P</transactionCode><equitySwapInvolved>0</equitySwapInvolved></transactionCoding><transactionAmounts><transactionShares><value>24000</value></transactionShares><transactionPricePerShare><value>0</value><footnoteId id="F3"/></transactionPricePerShare><transactionAcquiredDisposedCode><value>A</value></transactionAcquiredDisposedCode></transactionAmounts><exerciseDate><value>2003-10-13</value></exerciseDate><expirationDate><value>2008-10-13</value></expirationDate><underlyingSecurity><underlyingSecurityTitle><value>Common Stock</value></underlyingSecurityTitle><underlyingSecurityShares><value>24000</value></underlyingSecurityShares></underlyingSecurity><postTransactionAmounts><sharesOwnedFollowingTransaction><value>24000</value></sharesOwnedFollowingTransaction></postTransactionAmounts><ownershipNature><directOrIndirectOwnership><value>I</value></directOrIndirectOwnership><natureOfOwnership><value>See Note</value><footnoteId id="F4"/></natureOfOwnership></ownershipNature></derivativeTransaction></derivativeTable><footnotes><footnote id="F1">The reporting person may be deemed to be a member of a Section 13(d) group that owns more than 10% of the issuer's outstanding common stock.  The shares (other than shares held by Mr. Tang as custodian for a minor child) may be deemed to be beneficially owned by Tang Capital Partners, LP, Tang Capital Management, LLC (the general partner of Tang Capital Partners, LP) and Kevin C. Tang, the sole manager of Tang Capital Management, LLC.  Each of Tang Capital Management, LLC and Mr. Tang disclaims beneficial ownership of the shares except to the extent of its/his pecuniary interst therein.  The reporting persons disclaim beneficial ownership of the securities held by Kevin C. Tang as custodian for his minor child, and this report shall not be deemed as an admission that the beneficial owners of such securities for purporses of Section 16 or for any other purpose.</footnote><footnote id="F2">Includes 5,693 shares of common stock issued as a dividend on 6/30/03 and 2,778 shares of common stock issued as a dividend on 9/30/03, and 583 shares held by Kevin C. Tang as custodian for his minor child.</footnote><footnote id="F3">The reported securities are included with the shares of common stock purchased by the reporting person for $10.85 per share.  The number of warrant securities issued was determined by a formula based on the aggregate purchase price paid for the common stock.</footnote><footnote id="F4">The reporting person may be deemed to be a member of a Section 13(d) group that owns more than 10% of the issuer's outstanding common stock.  The securities may be deemed to be beneficially owned by Tang Capital Partners, LP, Tang Capital Management, LLC (the general partner of Tang Capital Partners, LP) and Kevin C. Tang, the sole manager of Tang Capital Management, LLC.  Each of Tang Capital Management, LLC and Mr. Tang disclaims beneficial ownership of the securities except to the extent of its/his pecuniary interst therein.  </footnote></footnotes><remarks/><ownerSignature><signatureName>Dennis Calderon, Attorney-in-fact</signatureName><signatureDate>2003-10-08</signatureDate></ownerSignature></ownershipDocument>

