144 0001193210 XXXXXXXX LIVE 0001232524 Jazz Pharmaceuticals Plc 001-33500 5th Floor Waterloo Exchange Waterloo Road Dublin L2 D04 E5W7 353-1-634-7800 Bruce C Cozadd Officer Common Merrill Lynch

3075A Hansen Way 1st Floor Palo Alto CA 94304

6000 1143010.3 61560350 04/01/2026 NASDAQ Common 01/03/2022 Stock Option Jazz Pharmaceuticals PLC N 1344 01/03/2022 Cash Common 01/03/2022 Stock Option Jazz Pharmaceuticals PLC N 3909 01/03/2022 Cash Common 02/01/2022 Stock Option Jazz Pharmaceuticals PLC N 747 02/01/2022 Cash N Bruce Cozadd

5th Floor Waterloo Exchange Waterloo Road Dublin L2 D04-E5W7

Common 03/03/2026 6000 1118613.32 04/01/2026 11/26/2025 Bruce C Cozadd